Rituximab exposure‐response in triweekly R‐CHOP treatment in DLBCL: A loading dose is recommended to improve clinical outcomes

• Main Authors: Shu Liu (Author), Zhao Wang (Author), Rongxin Chen (Author), He Huang (Author), Xueding Wang (Author), Chen Peng (Author), Yanping Guan (Author), Xiaojie Fang (Author), Shaoxing Guan (Author), Hongbing Huang (Author), Tao Liu (Author), Tongyu Lin (Author), Min Huang (Author)
• Format: Book
• Published: Wiley, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Previous exposure‐response analyses for rituximab suggest that higher rituximab concentrations were associated with an improvement in efficacy, however, clinical studies investigating a higher rituximab dose had mixed results. To further explore the exposure‐response relationship of rituxim...