Enhanced Antibacterial Activity of Dermaseptin through Its Immobilization on Alginate Nanoparticles-Effects of Menthol and Lactic Acid on Its Potentialization

• Main Authors: Noura Hazime (Author), Yanath Belguesmia (Author), Alexandre Barras (Author), Mohamed Amiche (Author), Rabah Boukherroub (Author), Djamel Drider (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dermaseptin B2 (DRS-B2) is an antimicrobial peptide secreted by <i>Phyllomedusa bicolor</i>, which is an Amazonian tree frog. Here, we show that the adsorption of DRS-B2 on alginate nanoparticles (Alg NPs) results in a formulation (Alg NPs + DRS-B2) with a remarkable antibacterial activi...