The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster
Aggregation of the amyloid-β peptide (Aβ) into toxic oligomers and amyloid fibrils is linked to the development of Alzheimer's disease (AD). Mutations of the BRICHOS chaperone domain are associated with amyloid disease and recent in vitro data show that BRICHOS efficiently delays Aβ42 oligomeri...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2014-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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