Closed-loop insulin delivery in pregnant women with type 1 diabetes (CRISTAL): a multicentre randomized controlled trial - study protocol

• Main Authors: Kaat Beunen (Author), Nancy Van Wilder (Author), Dominique Ballaux (Author), Gerd Vanhaverbeke (Author), Youri Taes (Author), Xavier-Philippe Aers (Author), Frank Nobels (Author), Joke Marlier (Author), Dahae Lee (Author), Joke Cuypers (Author), Vanessa Preumont (Author), Sarah E. Siegelaar (Author), Rebecca C. Painter (Author), Annouschka Laenen (Author), Pieter Gillard (Author), Chantal Mathieu (Author), Katrien Benhalima (Author)
• Format: Book
• Published: BMC, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Despite increasing use of continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII, insulin pumps) in type 1 diabetes (T1D) in pregnancy, achieving recommended pregnancy glycaemic targets (3.5-7.8 mmol/L or 63-140 mg/dL) remains challenging. Conseque...