Bioequivalence of a New Pediatric Paracetamol Oral Suspension Compared With a Marketed Formulation in Healthy Adults: A Randomized, Open-Label Study

• Main Authors: Jiri Grim, MD, PhD (Author), Marianna Armogida, MD (Author), Preeti Kachroo, BAMS, MD (AM) (Author), Kamran Siddiqui, MBBS, MBA (Author), Mauro Cavinato, PhD (Author), Mako Araga, MS (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: Background: A new oral paracetamol formulation with the same paracetamol quantity (24 mg/mL) as a marketed formulation but with finer active ingredient particle size and lower amounts of maltitol (5.85 g/dose in the test formulation vs 7.25 g/dose in the reference formulation) and sorbitol...