Formulation and pharmacokinetics of multi-layered matrix tablets: Biphasic delivery of diclofenac

• Main Authors: Ehab Mostafa Elzayat (Author), Ali Abdelzaher Abdel-Rahman (Author), Sayed Mohamed Ahmed (Author), Fars Kaed Alanazi (Author), Walid Abdulazim Habib (Author), Hisham Suliman Abou-Auda (Author), Adel Sakr (Author)
• Format: Book
• Published: Elsevier, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rapid availability of the drug at the site of action followed by maintaining its effect for a long period of time is of great clinical importance. Thus, the purpose of the present study was to prepare and evaluate multi-layered matrix tablets of diclofenac using Eudragit RL/RS blend to achieve b...