Effect of Native Gastric Mucus on in vivo Hybridization Therapies Directed at Helicobacter pylori

• Main Authors: Rita S Santos (Author), George R Dakwar (Author), Ranhua Xiong (Author), Katrien Forier (Author), Katrien Remaut (Author), Stephan Stremersch (Author), Nuno Guimarães (Author), Sílvia Fontenete (Author), Jesper Wengel (Author), Marina Leite (Author), Céu Figueiredo (Author), Stefaan C De Smedt (Author), Kevin Braeckmans (Author), Nuno F Azevedo (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H. pylori to antibiotics, antimicrobial nucleic acid mimics...