Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight

• Main Authors: Xiaorui Wu (Author), Dong Li (Author), Junlian Liu (Author), Lihong Diao (Author), Shukuan Ling (Author), Yuheng Li (Author), Jianyi Gao (Author), Quanchun Fan (Author), Weijia Sun (Author), Qi Li (Author), Dingsheng Zhao (Author), Guohui Zhong (Author), Dengchao Cao (Author), Min Liu (Author), Jiaping Wang (Author), Shuang Zhao (Author), Yu Liu (Author), Guie Bai (Author), Hongzhi Shi (Author), Zi Xu (Author), Jing Wang (Author), Chunmei Xue (Author), Xiaoyan Jin (Author), Xinxin Yuan (Author), Hongxing Li (Author), Caizhi Liu (Author), Huiyuan Sun (Author), Jianwei Li (Author), Yongzhi Li (Author), Yingxian Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing evidence indicates the occurrence of cognitive impairment in astronauts under spaceflight compound conditions, but the underlying mechanisms and countermeasures need to be explored. In this study, we found that learning and memory abilities were significantly reduced in rats under a simul...