A linked physiologically based pharmacokinetic model for hydroxychloroquine and metabolite desethylhydroxychloroquine in SARS‐CoV‐2(−)/(+) populations

• প্রধান লেখক: Claire Steinbronn (লেখক), Yashpal S. Chhonker (লেখক), Jenell Stewart (লেখক), Hannah Leingang (লেখক), Kate B. Heller (লেখক), Meighan L. Krows (লেখক), Michael Paasche‐Orlow (লেখক), Anna Bershteyn (লেখক), Helen C. Stankiewicz Karita (লেখক), Vaidehi Agrawal (লেখক), Miriam Laufer (লেখক), Raphael Landovitz (লেখক), Mark Wener (লেখক), Daryl J. Murry (লেখক), Christine Johnston (লেখক), Ruanne V. Barnabas (লেখক), Samuel L. M. Arnold (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2023-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Hydroxychloroquine (HCQ) is Food and Drug Administration (FDA)‐approved for malaria, systemic and chronic discoid lupus erythematosus, and rheumatoid arthritis. Because HCQ has a proposed multimodal mechanism of action and a well‐established safety profile, it is often investigated as a rep...