Development and application of neonatal physiology‐based pharmacokinetic models of amikacin and fosfomycin to assess pharmacodynamic target attainment

Abstract Antimicrobial resistance increasingly complicates neonatal sepsis in a global context. Fosfomycin and amikacin are two agents being tested in an ongoing multicenter neonatal sepsis trial. Although neonatal pharmacokinetics (PKs) have been described for these drugs, the physiological variabi...

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Main Authors: Christopher A. Darlow (Author), Neil Parrott (Author), Richard W. Peck (Author), William Hope (Author)
Format: Book
Published: Wiley, 2024-03-01T00:00:00Z.
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3rd Floor Main Library

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