Inhibition of GSK3β and RIP1K Attenuates Glial Scar Formation Induced by Ischemic Stroke via Reduction of Inflammatory Cytokine Production

• Main Authors: Jin Liu (Author), Yong-Ming Zhu (Author), Yi Guo (Author), Liang Lin (Author), Zhan-Xiang Wang (Author), Feng Gu (Author), Xin-Yi Dong (Author), Ming Zhou (Author), Yi-Fan Wang (Author), Hui-Ling Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the chronic phase following ischemic stroke, glial scars can prevent axonal regeneration and the intensification of inflammation. The protective effect of inhibition of glycogen synthase kinase-3β (GSK3β) or receptor-interacting protein 1 kinase (RIP1K) on ischemic stroke has been previously repo...