Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties

• Main Authors: Andrea Angeli (Author), Mariana Pinteala (Author), Stelian S. Maier (Author), Sonia Del Prete (Author), Clemente Capasso (Author), Bogdan C. Simionescu (Author), Claudiu T. Supuran (Author)
• 格式: 图书
• 出版: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• 主题: article
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A series of benzenesulfonamides incorporating selenazoles with diverse substitution patterns were investigated as inhibitors of six bacterial carbonic anhydrases (CAs, EC 4.2.1.1) from bacterial pathogens, such as Helicobacter pylori (hpCAα was the investigated enzyme), Vibrio cholerae (all the thre...