O-GlcNAcylation Is Required for the Survival of Cerebellar Purkinje Cells by Inhibiting ROS Generation

• Main Authors: Fengjiao Liu (Author), Shen Li (Author), Xin Zhao (Author), Saisai Xue (Author), Hao Li (Author), Guochao Yang (Author), Ying Li (Author), Yan Wu (Author), Lingling Zhu (Author), Liping Chen (Author), Haitao Wu (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purkinje cells (PCs), as a unique type of neurons output from the cerebellar cortex, are essential for the development and physiological function of the cerebellum. However, the intricate mechanisms underlying the maintenance of Purkinje cells are unclear. The O-GlcNAcylation (O-GlcNAc) of proteins...