O-GlcNAcylation Is Required for the Survival of Cerebellar Purkinje Cells by Inhibiting ROS Generation

• Главные авторы: Fengjiao Liu (Автор), Shen Li (Автор), Xin Zhao (Автор), Saisai Xue (Автор), Hao Li (Автор), Guochao Yang (Автор), Ying Li (Автор), Yan Wu (Автор), Lingling Zhu (Автор), Liping Chen (Автор), Haitao Wu (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2023-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Purkinje cells (PCs), as a unique type of neurons output from the cerebellar cortex, are essential for the development and physiological function of the cerebellum. However, the intricate mechanisms underlying the maintenance of Purkinje cells are unclear. The O-GlcNAcylation (O-GlcNAc) of proteins...