Curcumin prevents As3+-induced carcinogenesis through regulation of GSK3β/Nrf2

• Main Authors: Yuan-Ye Dang (Author), Hua Luo (Author), Yong-Mei Li (Author), Yang Zhou (Author), Xiu Luo (Author), Shui-Mu Lin (Author), Shou-Ping Liu (Author), Simon Ming-Yuen Lee (Author), Chu-Wen Li (Author), Xiao-Yan Dai (Author)
• Format: Book
• Published: BMC, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Arsenic (As3+) is a carcinogen with considerable environmental and occupational relevancy. Its mechanism of action and methods of prevention remain to be investigated. Previous studies have demonstrated that ROS is responsible for As3+-induced cell transformation, which is consid...