Alterations in Immune-Related Defensin Alpha 4 (DEFA4) Gene Expression in Health and Disease

• Main Authors: Fatemah Basingab (Author), Abeer Alsaiary (Author), Shahad Almontashri (Author), Aisha Alrofaidi (Author), Mona Alharbi (Author), Sheren Azhari (Author), Khloud Algothmi (Author), Safiah Alhazmi (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Defensin Alpha 4 (DEFA4) is the fourth member of the Alpha Defensins family known as a part of antimicrobial peptides in the innate immune system. DEFA4 has a strong preference to kill Gram-negative bacteria more than Gram-positive bacteria. In addition, DEFA4 exhibits antiviral activity against hum...