Experimental and Computational Observations of Immunogenic Cobalt Porphyrin Lipid Bilayers: Nanodomain-Enhanced Antigen Association

• Main Authors: Jasmin Federizon (Author), Conrard Giresse Tetsassi Feugmo (Author), Wei-Chiao Huang (Author), Xuedan He (Author), Kazutoyo Miura (Author), Aida Razi (Author), Joaquin Ortega (Author), Mikko Karttunen (Author), Jonathan F. Lovell (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cobalt porphyrin phospholipid (CoPoP) can incorporate within bilayers to enable non-covalent surface-display of antigens on liposomes by mixing with proteins bearing a polyhistidine tag (his-tag); however, the mechanisms for how this occurs are poorly understood. These were investigated using the hi...