The Activity of YCA1 Metacaspase Is Regulated by Reactive Sulfane Sulfur via Persulfidation in <i>Saccharomyces cerevisiae</i>

• Main Authors: Qingda Wang (Author), Xiaokun Zhang (Author), Zhuang Du (Author), Honglei Liu (Author), Yongzhen Xia (Author), Luying Xun (Author), Huaiwei Liu (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

YCA1, the only metacaspase in <i>Saccharomyces cerevisiae</i>, plays important roles in the regulation of chronological lifespan, apoptosis, and cytokinesis. YCA1 has protein hydrolase activity and functions by cleaving itself and target proteins. However, there are few reports about the...