Bupivacaine inhibits a small conductance calcium‐activated potassium type 2 channel in human embryonic kidney 293 cells

• मुख्य लेखकों: Hongfei Chen (लेखक), Zhousheng Jin (लेखक), Fangfang Xia (लेखक), Zhijian Fu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2021-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells and are involved in relevant physiological functions. However, whether b...