Integration of multiscale dendritic spine structure and function data into systems biology models

• Main Authors: James J Mancuso (Author), Jie eCheng (Author), Zheng eYin (Author), Jared C. Gilliam (Author), Xiaofeng eXia (Author), Xuping eLi (Author), Stephen T.C. Wong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Comprising 1011 neurons with 1014 synaptic connections the human brain is the ultimate systems biology puzzle. An increasing body of evidence highlights the observation that changes in brain function, both normal and pathological, consistently correlate with dynamic changes in neuronal anatomy. Anat...