Integration of multiscale dendritic spine structure and function data into systems biology models

• Główni autorzy: James J Mancuso (Autor), Jie eCheng (Autor), Zheng eYin (Autor), Jared C. Gilliam (Autor), Xiaofeng eXia (Autor), Xuping eLi (Autor), Stephen T.C. Wong (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2014-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Comprising 1011 neurons with 1014 synaptic connections the human brain is the ultimate systems biology puzzle. An increasing body of evidence highlights the observation that changes in brain function, both normal and pathological, consistently correlate with dynamic changes in neuronal anatomy. Anat...