Use of FLOSEAL® as a scaffold and its impact on induced neural stem cell phenotype, persistence, and efficacy

• 主要な著者: Hunter N. Bomba (著者), Abigail Carey‐Ewend (著者), Kevin T. Sheets (著者), Alain Valdivia (著者), Morgan Goetz (著者), Ingrid A. Findlay (著者), Alison Mercer‐Smith (著者), Lauren E. Kass (著者), Simon Khagi (著者), Shawn D. Hingtgen (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2022-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Induced neural stem cells (iNSCs) have emerged as a promising therapeutic platform for glioblastoma (GBM). iNSCs have the innate ability to home to tumor foci, making them ideal carriers for antitumor payloads. However, the in vivo persistence of iNSCs limits their therapeutic potential. We...