Human Placental Intracellular Cholesterol Transport: A Focus on Lysosomal and Mitochondrial Dysfunction and Oxidative Stress

• Main Authors: Maria Jose Yañez (Author), Andrea Leiva (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2022-03-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The placenta participates in cholesterol biosynthesis and metabolism and regulates exchange between the maternal and fetal compartments. The fetus has high cholesterol requirements, and it is taken up and synthesized at elevated rates during pregnancy. In placental cells, the major source of cholest...