Cavitation Feedback Control of Focused Ultrasound Blood-Brain Barrier Opening for Drug Delivery in Patients with Parkinson's Disease

• Main Authors: Yuexi Huang (Author), Ying Meng (Author), Christopher B. Pople (Author), Allison Bethune (Author), Ryan M. Jones (Author), Agessandro Abrahao (Author), Clement Hamani (Author), Suneil K. Kalia (Author), Lorraine V. Kalia (Author), Nir Lipsman (Author), Kullervo Hynynen (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Magnetic resonance-guided focused ultrasound (MRgFUS), in conjunction with circulating microbubbles, is an emerging technology that can transiently enhance the permeability of the blood-brain barrier (BBB) locally and non-invasively to facilitate targeted drug delivery to the brain. In this clinical...