Perspectives in modeling and model validation during analytical quality by design chromatographic method evaluation: a case study

• Main Authors: Yongzhi Dong (Author), Zhimin Liu (Author), Charles Li (Author), Emily Pinter (Author), Alan Potts (Author), Tanya Tadey (Author), William Weiser (Author)
• Format: Bog
• Udgivet: SpringerOpen, 2021-09-01T00:00:00Z.
• Fag: article
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Abstract Design of experiments (DOE)-based analytical quality by design (AQbD) method evaluation, development, and validation is gaining momentum and has the potential to create robust chromatographic methods through deeper understanding and control of variability. In this paper, a case study is use...