Effects of Heat Shock Protein 90 Inhibition In the Lungs

• Główni autorzy: Mohammad A. Uddin (Autor), Khadeja-Tul Kubra (Autor), Jafrin Jobayer Sonju (Autor), Mohammad S. Akhter (Autor), Jois Seetharama (Autor), Nektarios Barabutis (Autor)
• Format: Książka
• Wydane: Elsevier, 2020-06-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Inhibition of Hsp90 is associated with anti-inflammatory effects. We employed human lung microvascular endothelial cells to investigate the effects of the Hsp90 inhibitors 17-AAG, AUY-922 and 17-DMAG in the unfolded protein response (UPR) and viability of lung cells. Our observations indicate that m...