Effect of exercise on HIF-1 and VEGF signaling

• Main Authors: Hideki Ohno (Author), Ken Shirato (Author), Takuya Sakurai (Author), Junetsu Ogasawara (Author), Yoshikazu Sumitani (Author), Shogo Sato (Author), Kazuhiko Imaizumi (Author), Hitoshi Ishida (Author), Takako Kizaki (Author)
• Format: Book
• Published: Japanese Society of Physical Fitness and Sports Medicine, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This review summarizes the literature describing the significance of various conditions, such as hypoxia, oxidative stress, and, above all, physical exercise, in the hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) signaling pathway mainly in skeletal muscle. HIF-1α a...