Inhibiting the Growth of 3D Brain Cancer Models with Bio-Coronated Liposomal Temozolomide

• Main Authors: Giordano Perini (Author), Francesca Giulimondi (Author), Valentina Palmieri (Author), Alberto Augello (Author), Luca Digiacomo (Author), Erica Quagliarini (Author), Daniela Pozzi (Author), Massimiliano Papi (Author), Giulio Caracciolo (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanoparticles (NPs) have emerged as an effective means to deliver anticancer drugs into the brain. Among various forms of NPs, liposomal temozolomide (TMZ) is the drug-of-choice for the treatment and management of brain tumours, but its therapeutic benefit is suboptimal. Although many possible reaso...