Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis.

• Main Authors: Alexander F Flynn (Author), M Gordon Joyce (Author), Rebekah T Taylor (Author), Sasisekhar Bennuru (Author), Alyssa R Lindrose (Author), Spencer L Sterling (Author), C Paul Morris (Author), Thomas B Nutman (Author), Edward Mitre (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lymphatic filariasis (LF), a morbid disease caused by the tissue-invasive nematodes Wuchereria bancrofti, Brugia malayi, and Brugia timori, affects millions of people worldwide. Global eradication efforts have significantly reduced worldwide prevalence, but complete elimination has been hampered by...