Pharmacological Characterization of Toludesvenlafaxine as a Triple Reuptake Inhibitor

• Main Authors: Haibo Zhu (Author), Wenyan Wang (Author), Chunjie Sha (Author), Wei Guo (Author), Chunmei Li (Author), Fengjuan Zhao (Author), Hongbo Wang (Author), Wanglin Jiang (Author), Jingwei Tian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toludesvenlafaxine hydrochloride dihydrate is a novel chemical entity and a potential triple monoamine reuptake inhibitor. This study characterized the in vitro triple reuptake inhibition activity, antidepressant-like activity in animals, and pharmacokinetic profiles in rats of toludesvenlafaxine. B...