Population pharmacokinetics of nalbuphine in patients undergoing general anesthesia surgery

• Main Authors: Xuyang Nie (Author), Xiaonan Gao (Author), Jinglin Gao (Author), Tianfang Heng (Author), Yuqi Zhang (Author), Yaqi Sun (Author), Zhangying Feng (Author), Li Jia (Author), Mingxia Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The aim of this study was to build a population pharmacokinetics (PopPK) model of nalbuphine and to estimate the suitability of bodyweight or fixed dosage regimen.Method: Adult patients who were undergoing general anesthetic surgery using nalbuphine for induction of anesthesia were included...