Inhibition of P38 MAPK Downregulates the Expression of IL-1β to Protect Lung from Acute Injury in Intestinal Ischemia Reperfusion Rats

• Main Authors: De-Yi Zheng (Author), Min Zhou (Author), Jiao Jin (Author), Mu He (Author), Yi Wang (Author), Jiao Du (Author), Xiang-Yang Xiao (Author), Ping-Yang Li (Author), Ai-Zhu Ye (Author), Jia Liu (Author), Ting-Hua Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) induced by intestinal ischemia/reperfusion (II/R) has high incidence and mortality, in which IL-1β was essential for the full development of ALI. However, the detailed regulating mechanism for this phenomenon remains to be unclear. The purpose of this study was to investigate...