Autoimmune polyglandular syndrome type 1: a case report and brief review

• Main Authors: Ifeanyi Nwosu (Author), Oreoluwa Oladiran (Author), Chinyere Ogbonna-Nwosu (Author), Anulika Anyata (Author)
• Format: Book
• Published: Greater Baltimore Medical Center, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Autoimmune polyglandular syndrome (APS) type 1 is a rare autoimmune disorder inherited in an autosomal recessive pattern due to loss of function of the AIRE gene and defective removal of self-reactive T-lymphocytes during the process of thymic T cell maturation. Its manifestation starts early in lif...