Effect of X-ray radiation on the pharmacokinetics of apatinib in vivo in rats

• Main Authors: Shi-Qi Dong (Author), Fan Yang (Author), Dong-Xu Zhang (Author), Ling-Mei Wang (Author), Jian-Feng Liu (Author), Ai-Jie Zhang (Author), Hui-Rong Fan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The "radiotherapy-pharmacokinetic" ("RT-PK") phenomenon refers to the fact that radiation can significantly alter the pharmacokinetic behavior of a drug. At present, it is not clear whether there is an "RT-PK" phenomenon that can affect apatinib during concurre...