Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase

Inorganic anions inhibit the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1) generally by coordinating to the active site metal ion. Cyanate was reported as a non-coordinating CA inhibitor but those erroneous results were subsequently corrected by another group. We review the anion CA inhibitors (...

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Main Authors: Alessio Nocentini (Author), Andrea Angeli (Author), Fabrizio Carta (Author), Jean-Yves Winum (Author), Raivis Zalubovskis (Author), Simone Carradori (Author), Clemente Capasso (Author), William A. Donald (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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