Involvement of TRPM7 in Cell Growth as a Spontaneously Activated Ca2+ Entry Pathway in Human Retinoblastoma Cells

• Main Authors: Toyohisa Hanano (Author), Yuji Hara (Author), Juan Shi (Author), Hiromitsu Morita (Author), Chisato Umebayashi (Author), Emiko Mori (Author), Hideki Sumimoto (Author), Yushi Ito (Author), Yasuo Mori (Author), Ryuji Inoue (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the possible involvement of the melastatin family protein TRPM7 in Ca2+-mediated proliferative control of human retinoblastoma (RB) cells. The growth of RB cell was facilitated by elevating the extracellular Ca2+ concentration with a parallel increase in the magnitude of spontaneous...