Nitroxyl: A Novel Strategy to Circumvent Diabetes Associated Impairments in Nitric Oxide Signaling

• Autori principali: Anida Velagic (Autore), Chengxue Qin (Autore), Owen L. Woodman (Autore), John D. Horowitz (Autore), Rebecca H. Ritchie (Autore), Barbara K. Kemp-Harper (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Diabetes is associated with an increased mortality risk due to cardiovascular complications. Hyperglycemia-induced oxidative stress underlies these complications, leading to an impairment in endogenous nitric oxide (NO•) generation, together with reductions in NO• bioavailability and NO• responsiven...