Gel formulated with Bryophyllum pinnatum leaf extract promotes skin wound healing in vivo by increasing VEGF expression: A novel potential active ingredient for pharmaceuticals

• Main Authors: Edilane Rodrigues Dantas Araújo (Author), Jacinthia Beatriz Xavier-Santos (Author), Valéria Costa da Silva (Author), Juliana Bessa Figueiredo de Lima (Author), Jade Schlamb (Author), Matheus de Freitas Fernandes-Pedrosa (Author), Arnóbio Antônio da Silva Júnior (Author), Raimundo Fernandes de Araújo Júnior (Author), Thirumurugan Rathinasabapathy (Author), Marvin Moncada (Author), Debora Esposito (Author), Gerlane Coelho Bernardo Guerra (Author), Silvana Maria Zucolotto (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bryophyllumpinnatum (Crassulaceae) is used in traditional medicine for treating skin wounds. In our previous study, a topical gel containing B. pinnatum aqueous leaf extract showed a preclinical anti-inflammatory effect in in vivo acute edema models. In continuation, the present study aims to evalua...