Immune-engineered H7N9 influenza hemagglutinin improves protection against viral influenza virus challenge

• Hlavní autoři: Hyesun Jang (Autor), Lauren M. Meyers (Autor), Christine Boyle (Autor), Anne S. De Groot (Autor), Lenny Moise (Autor), Ted M. Ross (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2020-09-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

The influenza hemagglutinin (HA) isolated from avian H7N9 influenza virus strains elicit weak immune responses. This low immunogenicity may be due to a regulatory T cell (Treg)-stimulating epitopes in HA from the H7N9 isolate A/Anhui/1/2013 (Anh/13). In this report, this Treg stimulating sequence wa...