Investigation of the inhibitory effects of HA-1077 and Y-32885 on the translocation of PKCβI, PKCβII and PKCζ in human neutrophils

• Main Authors: Xavier Siomboing (Author), Bernard Gressier (Author), Thierry Dine (Author), Claude Brunet (Author), Michel Luyckx (Author), Michelene Cazin (Author), Jean-Claude Cazin (Author)
• Format: Book
• Published: Hindawi Limited, 2001-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To transmit the information inside the cell, one possibility is the action of an enzyme called kinase that phosphorylates other proteins. To study these enzymes, chemical compound synthesis was needed to know the function and the mechanism of activation. The major difficulty is creating a specific m...