3H-1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors

3H-1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors

A new chemotype with carbonic anhydrase (CA, EC 4.2.1.1) inhibitory action has been discovered, the homo-sulfocoumarins (3H-1,2-benzoxathiepine 2,2-dioxides) which have been designed considering the (sulfo)coumarins as lead molecules. An original synthetic strategy of a panel of such derivatives led...

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Main Authors: Aleksandrs Pustenko (Author), Dmitrijs Stepanovs (Author), Raivis Žalubovskis (Author), Daniela Vullo (Author), Andris Kazaks (Author), Janis Leitans (Author), Kaspars Tars (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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