Cyclooxygenase-2 inhibitors: promise or peril?

• Main Authors: Laurel J. Mengle-Gaw (Author), Benjamin D. Schwartz (Author)
• Format: Knjiga
• Izdano: Hindawi Limited, 2002-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

The discovery of two isoforms of the cyclooxygenase enzyme, COX-1 and COX-2, and the development of COX-2-specific inhibitors as anti-inflammatories and analgesics have offered great promise that the therapeutic benefits of NSAIDs could be optimized through inhibition of COX-2, while minimizing thei...