A novel method for evaluating activity of transient receptor potential channels using a cellular dielectric spectroscopy

• Main Authors: Kanako Miyano (Author), Katsuya Ohbuchi (Author), Yuka Sudo (Author), Kouichiro Minami (Author), Toru Yokoyama (Author), Masahiro Yamamoto (Author), Miaki Uzu (Author), Miki Nonaka (Author), Seiji Shiraishi (Author), Hiroaki Murata (Author), Yoshikazu Higami (Author), Yasuhito Uezono (Author)
• Format: Book
• Published: Elsevier, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cellular dielectric spectroscopy (CDS) is a novel technology enabling pharmacological evaluation of multiple receptor types with a label-free cell-based assay. We evaluated activities of a family of ligand-gated channels, transient receptor potential vanilloid 1 (TRPV1) and transient receptor potent...