Optimized Polyethylene Glycolylated Polymer-Lipid Hybrid Nanoparticles as a Potential Breast Cancer Treatment

• Main Authors: Salam Massadeh (Author), Mustafa E Omer (Author), Asmaa Alterawi (Author), Rizwan Ali (Author), Fayez H Alanazi (Author), Fares Almutairi (Author), Wejdan Almotairi (Author), Faris F Alobaidi (Author), Khulud Alhelal (Author), Mansour S Almutairi (Author), Abdulaziz Almalik (Author), Aiman A. Obaidat (Author), Manal Alaamery (Author), Alaa Eldeen Yassin (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The aim of this work is to optimize a polyethylene glycolated (PEGylated) polymer-lipid hybrid nanoparticulate system for the delivery of anastrozole (ANS) to enhance its biopharmaceutical attributes and overall efficacy. Methods: ANS loaded PEGylated polymer-lipid hybrid nanoparticles (PLN...