Glyoxalase System as a Therapeutic Target against Diabetic Retinopathy

• Ngā kaituhi matua: Gemma Aragonès (Author), Sheldon Rowan (Author), Sarah G Francisco (Author), Wenxin Yang (Author), Jasper Weinberg (Author), Allen Taylor (Author), Eloy Bejarano (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2020-10-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Hyperglycemia, a defining characteristic of diabetes, combined with oxidative stress, results in the formation of advanced glycation end products (AGEs). AGEs are toxic compounds that have adverse effects on many tissues including the retina and lens. AGEs promote the formation of reactive oxygen sp...