Clustered regularly interspaced short palindromic repeats screens in pediatric tumours: A review

• Main Authors: Madelaine G. vanMackelenbergh (Author), Dennis S. Metselaar (Author), Michaël H. Meel (Author), Esther Hulleman (Author)
• Format: Knjiga
• Izdano: Wiley, 2022-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract In recent years, the discovery and development of clustered regularly interspaced short palindromic repeats (CRISPR) technology has revolutionized and accelerated functional genetic screening in cancer research. In this review, we discuss different methods of executing CRISPR screens, with...