EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers

• Main Authors: Marco Papale (Author), Elisabetta Ferretti (Author), Giuseppe Battaglia (Author), Diana Bellavia (Author), Antonello Mai (Author), Marco Tafani (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During the past decades, several discoveries have established the role of epigenetic modifications and cellular microenvironment in tumor growth and progression. One of the main representatives concerning epigenetic modification is the polycomb group (PcG). It is composed of different highly conserv...