Poly-ε-caprolactone based nanoparticles for delivery of genistein in melanoma treatment

• Main Authors: Juliana Palma Abriata (Author), Marcela Tavares Luiz (Author), Juliana Santos Rosa Viegas (Author), Fernando Fumagalli (Author), Shaiani Maria Gilde Melo (Author), Flavio da Silva Emery (Author), Juliana Maldonado Marchetti (Author), Fabiana Testa Moura de Carvalho Vicentini (Author)
• Format: Book
• Published: Universidade de São Paulo, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We developed poly-ε-caprolactone (PCL)-based nanoparticles containing D-α-tocopherol polyethylene glycol-1000 succinate (TPGS) or Poloxamer 407 as stabilizers to efficiently encapsulate genistein (GN). Two formulations, referred to as PNTPGS and PNPol, were prepared using nanoprecipitation....