Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis

• Main Authors: Yen Ching Lim (Author), Sook Yoong Chia (Author), Shengnan Jin (Author), Weiping Han (Author), Chunming Ding (Author), Lei Sun (Author)
• Format: Book
• Published: Elsevier, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: DNA methylation may be a stable epigenetic contributor to defining fat cell lineage. Methods: We performed reduced representation bisulfite sequencing (RRBS) and RNA-seq to depict a genome-wide integrative view of the DNA methylome and transcriptome during brown and white adipogenesis. Re...