The Pathological Mechanisms of Estrogen-Induced Cholestasis: Current Perspectives

• Autori principali: Yue Zu (Autore), Jinyu Yang (Autore), Chengliang Zhang (Autore), Dong Liu (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Estrogens are steroid hormones with a wide range of biological activities. The excess of estrogens can lead to decreased bile flow, toxic bile acid (BA) accumulation, subsequently causing intrahepatic cholestasis. Estrogen-induced cholestasis (EIC) may have increased incidence during pregnancy, and...