Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect

• Main Authors: Xia Niu (Author), Xiaomei Wang (Author), Bingyu Niu (Author), Yanan Meng (Author), Hongwei He (Author), Yucheng Wang (Author), Guiling Li (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver fibrosis remains a significant public health problem. However, few drugs have yet been validated. Costunolide (COS), as a monomeric component of the traditional Chinese medicinal herb <i>Saussurea Lappa</i>, has shown excellent anti-fibrotic efficacy. However, COS displays very poo...